Jenkins played FBI agent Leyla Harrison in The X-Files, Diana in Shasta McNasty, and the character "Deirdre" in Desperate Housewives. Jenkins and fellow The X-Files cast member Annabeth Gish both appeared in the 2002 movie Buying the Cow as well as both appearing in The West Wing.
Not much is known about Jenkins's personal life. Jenkins's adoptive father is famed personal development coach Tony Robbins. She is married to producer David Pagani.